The Perfect Rome to Florence Day Trip: Attractions to See, One Day Florence Itinerary, Tours and Tips for an Epic Trip!

Florence, the capital of Tuscany, is often considered the birthplace of the Renaissance and an iconic destination for art lovers, history enthusiasts, and travelers seeking a mix of culture and beauty. Having spent two weeks in Florence last summer, I completely fell in love with its timeless charm. This wasn’t my first visit to the city, but every time I return, it feels like I’m discovering something new and exciting. Whether you’re a first-timer or returning for the second or third time, Florence offers a unique experience that captures the heart.
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Florence vs. Rome
Comparing Florence to Rome is like comparing two sides of the same coin—both cities are rich in history, art, and culture, but Florence is a smaller, more compact treasure trove that feels more like a living museum. While Rome’s grandeur and ancient ruins impress with their massive scale, Florence invites you into a more intimate, refined atmosphere where art and beauty are on every corner. Rome offers grand monuments like the Colosseum and the Pantheon, while Florence lures visitors with its art-filled museums, piazzas, and quaint charm. Florence may be smaller in size, but it’s brimming with the kind of iconic sites and hidden gems that make it a must-see destination.
Why Visit Florence?
Florence is one of the most artistic cities in the world, home to priceless masterpieces by Michelangelo, Leonardo da Vinci, Botticelli, and more. Whether you’re an art lover or just appreciate good food and great views, Florence offers an enriching experience for everyone. The city is renowned for its museums, art galleries, stunning architecture, and delicious Tuscan cuisine.
What is Florence Famous For?
Florence is famous for its Renaissance art and architecture. The city is home to iconic landmarks like the Florence Cathedral (Duomo), Michelangelo’s David, and the Uffizi Gallery. The historic center, a UNESCO World Heritage Site, is filled with breathtaking buildings, bridges, and squares, creating an open-air museum that you can explore on foot.
Where is Florence?
Florence is located in central Italy, in the region of Tuscany. It’s a picturesque city set along the Arno River, surrounded by rolling hills and vineyards, making it a perfect base for exploring the Tuscan countryside as well.
How Far is Florence from Rome?
Florence is approximately 275 kilometers (170 miles) north of Rome. The travel time between the two cities varies depending on your mode of transportation, but it typically takes around 1.5 to 2.5 hours.
How to Get to Florence from Rome
There are several ways to travel from Rome to Florence:
- By Train: The train is one of the quickest and most convenient ways to travel between Rome and Florence. High-speed trains (Frecciarossa or Italo) can get you to Florence in about 1.5 hours. Trains depart regularly from Roma Termini Station (Rome’s main train station) and arrive at Firenze Santa Maria Novella Station (Florence’s central station). One-way Rome-Florence train tickets are €15 on average if bought in advance.
- By Bus: Traveling by bus takes longer, around 3-4 hours, but can be a more economical option. Buses depart from Rome’s Tiburtina Bus Station and arrive at Florence’s Central Bus Station (Villa Costanza), which is located just outside the city center (12.1 km from the city center). One-way bus tickets from Rome to Florence start at €5.97.
- By Car: If you prefer driving, the distance by car is around 275 kilometers, and it will take you around 3 hours to reach Florence, depending on traffic. The drive offers beautiful views of the Italian countryside, so it’s a great option for those who enjoy road trips. I enjoy driving in Italy and always rent cars online through Discover Car Hire.
- By Tour: Many tour companies offer day trips from Rome to Florence, which can be a convenient choice if you prefer a guided experience. These tours often include transportation, a local guide, and a structured itinerary, like this Day Trip to Florence by High-Speed Train or the Florence Day Trip from Rome with Lunch.
Getting Around in Florence
- From Rome Central Bus Station to Florence Central Bus Station: If you’re traveling by bus, you will depart from Tiburtina Bus Station in Rome and arrive at Villa Costanza Bus Station in Florence. From here, take a tram T1.3 to the city center.
- From Rome Central Train Station to Florence Central Train Station: Trains depart from Roma Termini Station and arrive at Firenze Santa Maria Novella Station. The journey takes about 1.5 hours, and the train station is located in the heart of Florence, making it easy to walk to the city’s main attractions.
- Where to Park in Florence: Florence’s city center is a restricted traffic zone (ZTL), so parking can be tricky. However, there are several parking garages and lots just outside the center, such as:
- Parcheggio Sant’Ambrogio – a perfectly located and fairly priced underground parking lot near the city center. It can be busy and hard to find a free parking lot.
- Parcheggio Fortezza Fiera – a huge parking place with many parking lots, located only 15 minutes walk from te city center.
- Parcheggio Porta al Prato– an underground parking garage, inexpensive and only 20 minutes walk from the city center.

How to Spend One Day in Florence: A Perfect Itinerary
If you are making a quick Rome to Florence day trip, here’s a perfect itinerary to experience the best of the city:
1. Morning – Explore the Cathedral of Florence Complex (Duomo)
The Florence Cathedral (Cattedrale di Santa Maria del Fiore) is an architectural masterpiece and one of the most iconic landmarks in Italy. The cathedral, with its stunning Brunelleschi’s Dome, dominates the city’s skyline. You can purchase a Brunelleschi Pass, which allows you to explore the Cathedral, climb to the top of the Dome, and visit the Baptistery and the Museum of the Opera del Duomo.
Pro Tip:
Arrive as early in the morning as possible to beat the crowds, especially if you plan to climb Brunelleschi’s Dome. The climb to the top involves 463 steps, so be prepared! Also, check if there’s a specific time slot for your visit—this is especially important for the dome and other parts of the complex.
Ticket & Opening Times:
- The Brunelleschi Pass costs around €18, covering the Cathedral, Dome, Crypt, Baptistery, and the Bell Tower. This Cathedral & Brunelleschi’s Dome Ticket & Audio App is a great buy!
- Opening hours: 10:00 AM – 5:00 PM (closed on the first Tuesday of each month).


2. Visit the Academy Gallery to See Michelangelo’s David
The Accademia Gallery is home to one of the most famous sculptures in the world, Michelangelo’s David. Standing at over 17 feet tall, this Renaissance masterpiece is a symbol of strength and beauty. The gallery also displays other works by Michelangelo, as well as art from the 14th to the 16th century.
Pro Tip:
The Michelangelo’s David Priority Ticket & Audio App is a great way to skip the lines and get an enriching commentary on the art. As the Accademia Gallery can get busy, consider visiting either early in the morning or later in the afternoon to avoid the peak crowds. Spend time appreciating the other works around David to fully understand the context of the statue.
Ticket & Opening Times:
- Opening hours: 8:15 AM – 6:50 PM (closed on Mondays).
- Michelangelo’s David Priority Ticket: Approximately €16.

3. Lunch – Mercato Centrale
For lunch, head to the Mercato Centrale, a bustling indoor food market where you can experience the heart of Tuscan cuisine. The market is divided into two levels: one for fresh food and local produce, and the other for gourmet food stalls offering a range of Italian dishes.
I highly recommend trying fresh pasta at Pasta Fresca or a traditional Florentine sandwich at All’Antico Vinaio. For dessert, treat yourself to gelato or tiramisu from one of the food stalls.
Pro Tip:
If you’re short on time but still want to experience Mercato Centrale, head to the second floor where there are multiple food vendors offering quick, delicious meals. If you’re there during lunchtime, it can get crowded, so opt for a seat at one of the communal tables or grab a bite to eat standing at one of the counters.
4. Early Afternoon – Santa Maria Novella Basilica
After lunch, walk over to Santa Maria Novella Basilica, one of Florence’s most significant churches. This stunning church is known for its intricate frescoes, including works by Ghirlandaio and Masaccio, and its beautiful Gothic and Renaissance-style facade. The interior is equally breathtaking, with its peaceful atmosphere and beautifully preserved art.
Pro Tip: Many visitors overlook this gem due to its location, but it’s definitely worth a visit. If you want a peaceful experience, try visiting during midday when many tourists are out having lunch.
Ticket & Opening Times:
- Entry fee: Around €7 for general admission.
- Opening hours: 9:00 AM – 5:30 PM.

5. Late Afternoon – Piazza della Signoria & Palazzo Vecchio
After exploring Santa Maria Novella, head to the Piazza della Signoria, the most famous square in Florence. Here, you’ll find the majestic Palazzo Vecchio, a fortress-like town hall, and outdoor sculptures like a replica of Michelangelo’s David. The square is often bustling with both locals and tourists, giving it a vibrant, lively atmosphere.
Pro Tip: Take a moment to sit on the steps of the Palazzo Vecchio and soak in the views of the square. For the best photos, visit in the late morning or early afternoon when the sunlight bathes the sculptures and buildings in a golden glow.
Recommendation: If you have extra time, take a short tour of the Palazzo Vecchio to see the grand halls, art collections, and stunning views from the top of the tower.

6. Early Evening – Tour the Uffizi Gallery
Next item on your Rome to Florence day trip is the Uffizi Gallery, one of the most important art museums in the world. It houses works by some of the greatest Renaissance artists, including Botticelli’s The Birth of Venus, Leonardo da Vinci’s Annunciation, and Michelangelo’s The Holy Family. The museum offers a comprehensive journey through the history of Western art, and each room holds something special.
Pro Tip: The Uffizi is huge, so it’s a good idea to book a skip-the-line ticket or consider a guided tour if you want a more in-depth experience. If you prefer to take your time, plan to spend at least 2-3 hours here.
Ticket & Opening Times:
- Skip-the-Line Uffizi Ticket: Around €20.
- Opening hours: 8:15 AM – 6:50 PM (closed on Mondays).


7. Sunset – Piazzale Michelangelo
After a day of exploring museums and historical sites, head to Piazzale Michelangelo for one of the most breathtaking views of Florence. Located on a hilltop just outside the city center, Piazzale Michelangelo offers a panoramic view of Florence, with the Arno River winding through the city and the iconic Duomo in the distance.
Pro Tip: Arrive at Piazzale Michelangelo at least 30 minutes before sunset to grab a good spot and enjoy the changing colors of the sky over Florence. The view is stunning, so be sure to bring your camera!
8. Dinner – Enjoy Tuscan Cuisine
End your Rome to Florence day trip with a delicious dinner at Trattoria 13 Gobbi. This charming, traditional trattoria is a local favorite, offering authentic Tuscan cuisine in a warm and welcoming atmosphere. It’s located a bit off the beaten path, which makes it a great choice for a more relaxed, authentic dining experience. Try their pappardelle al cinghiale and bistecca alla Fiorentina and for dessert, order cantucci with vin santo (the iconic Tuscan almond biscuits dipped in Vin Santo, a sweet dessert wine).
Pro tip: Trattoria 13 Gobbi is a popular spot among locals, so make sure to book a reservation in advance, especially if you’re visiting during the high season. The cozy, rustic interior adds to the charm, making it a lovely place to relax after a busy day of sightseeing.
Location: Via del Porcellana, 9/r, 50123 Firenze FI, Italy.
Recommended Tickets and Tours in Florence
- Florence: Cathedral & Brunelleschi’s Dome Ticket & Audio App (valid 1-3 days)
- Florence: Michelangelo’s David Priority Ticket & Audio App (valid 1 day)
- Florence: Skip-The-Line Uffizi Gallery Timed Entry Ticket (valid 1 day)
- Florence: Guided Walking Tour (1.5 hours)
- Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine (3 hours)
Where to Stay in Florence
If you decide to stay longer in Florence, consider booking a room at the Grand Hotel Cavour. This luxurious hotel offers a perfect blend of historic charm and modern comfort, with fantastic views of the city and easy access to Florence’s top attractions.
Tips for Visiting Florence
- Wear Comfortable Shoes: Florence is best explored on foot, so make sure to bring comfortable shoes for walking.
- Buy Tickets in Advance: Popular attractions like the Uffizi Gallery and the Cathedral can get crowded, so booking tickets in advance is a good idea.
- Be Prepared for the Crowds at the Piazzale Michelangelo at Sunset: This sunset viewpoint in Florence is highly popular. So, be prepared for the crowds.
- Take Time to Wander: While Florence’s main attractions are a must-see, don’t forget to wander through its charming streets, discover hidden squares, and enjoy the city’s wonderful atmosphere.
Is a Rome to Florence Day Trip Worth It?
Absolutely! While one day is not enough to explore everything Florence has to offer, a day trip will give you a taste of its incredible art, culture, and beauty. If you’re in Rome and have the time, a Florence day trip is an unforgettable experience that will leave you longing for more.
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